Main information about Ativan
Ativan is an anxiolytic derived from benzodiazepine. It contains Lorazepam that differs from most benzodiazepines by low toxicity and broad therapeutic action.
Ativan provides a sedative, myorelaxing, anticonvulsive, anti-anxious action. The whole pharmacological activity is related to the increase of the sensitivity of the central nervous system to the action of gamma-aminobutyric acid.
Using Ativan significantly reduces an agitation of the central nervous system and inhibits hypernormal reflexes. In 1-2 weeks of the treatment, fear, anxiety, emotional tension are decreased, sleep is improved, muscle cramps disappear, and tone of skeletal muscles is reduced.
The studies have shown that Ativan similarly acts to all functions of the central nervous system and does not give more sedative or anti-anxious characteristics. This drug has a moderate action that appears regardless of the type of pathology in the central nervous system.
Ativan may be used during neuroses, generalized anxious disorder, phobia, emotional reactive disorders, psychosomatic disorders, abstinent syndrome during chronic alcoholism, and others.
It has been also detected that metabolites of Ativan do not cause unexpected severe side effects which are peculiar to all benzodiazepines. The frequency of the side effects is lower during the use of the drug, and it means that the treatment is higher.
Administration and usage of Ativan
To treat neuroses and emotional disorders, patients should take a pill of Ativan 1 mg 2-3 times per day within 3-4 weeks.
To treat psychosomatic disorders, anxiety and panic disorders, Ativan 1 mg is used 4 times per day within 4-6 weeks. The maximal daily dose is 6 mg.
If insomnia caused by the neurological or mental disorders, Ativan 1 mg is used 30 minutes before sleeping. If the effect is weak, the dose may be increased up to 2 mg.
The Ativan pills may be used before and after meals. Every pill is used with water and swallowed entirely. Do not break and do not add it to food. This may decrease a therapeutic effect.
Recommendations for the use
- Using Ativan within more than 6-7 weeks may develop a tolerance and a medical addition. If the treatment is ineffective, have an additional examination and change a scheme of the treatment
- Avoid alcohol consumption during the use of Ativan and within 15-20 days after the end of the treatment
- Any sedative drugs, alcohol, opioid analgesics and other drugs affective the central nervous system increase the action of Ativan. Keep this in mind and avoid such medical interaction
- Patients with depression should carefully take Ativan taking into account a tendency to suicide
- The use of Ativan is contraindicated during hepatic failure, pregnancy, glaucoma, and respiratory distress
The side effects of Ativan are usually observed at the beginning of the therapy. This may be lack of energy, fatigue, drowsiness, dizziness, depression, nausea, and vomiting. A regular use of the pills lower the degree of the side effects.
Take into account a possibility of the more frequent appearance of the side effects in senior and impaired patients.