Main information about Cephalexin

Cephalexin is an antibacterial medicine from the group of cephalosporin of the first generation.

A group of the antibiotic is very important in the medical practice because its pharmacological activity depends on it.

Cephalosporin are similar to penicillin but have a higher resistance to the action of beta-lactamase.

Cephalexin provides a bactericidal action as to gram-positive and gram-negative microorganisms.

A mechanism of this action is related to the affection of the cellular wall of bacteria.

Cephalexin also favors a release of autolytic enzymes which cause death of the microorganisms.

Cephalexin may be called a classical antibacterial drug which can be used in the treatment of many diseases:

  • Infections of the genitourinary system: cystitis, prostatitis, urethritis, pyelonephritis
  • Infections of the respiratory tract: bronchitis, tracheitis, pneumonia
  • Skin Infections: abscess, erysipelas, acne, furunculosis
  • Bone Infections: Osteomyelitis.

Cephalexin is not notable for any special pharmacological features among other antibiotics. It is quickly absorbed into the blood plasma and a peak of the concentration is observed in an hour. Cephalexin is evenly spread in the tissues.

The high concentrations are noticed in all organs, and a stable antibacterial effect is observed.

Administration and dose of Cephalexin

To treat infections in adults and teenagers over 12 years old, Cephalexin is used in the pills for the oral use. It should be used 30-45 minutes before meals with a glass of water.

The pills of Cephalexin 250-500 mg are taken every 6 hours (4 times per day) within at least 7 days. A standard therapeutic daily dose of Cephalexin is 1000-2000 mg during infections of the middle severity. If a severe acute infection has been diagnosed, a daily dose of Cephalexin may be increased up to 4000 mg.

Children under 12 years old are prescribed Cephalexin suspensions.

Recommendations for the use

  • Patients with kidney dysfunctions adjust the dose depending on the clearance of creatinine
  • Beverage drinks are prohibited during the treatment because the drug is incompatible with ethanol
  • Cephalexin is not prescribed with chloramphenicol and antibiotics from tetracycline group
  • Cephalexin does not have contraindications but it is not recommended during hypersensitivity to beta-lactamase antibiotics (any)
  • Doctors do not recommend to take Cephalexin during pregnancy, lactation, but if there are no other options for the treatment of the infectious disease, the antibiotic is prescribed under doctor’s supervision

Side effect

A side effect of Cephalexin is a common thing for an antibacterial drug: weakness, headache, abdominal pain, dry mouth, decreased appetite, nausea, itching, and genital candidiasis.

A development of the side effect may tell about high daily dose of Cephalexin for your body. consult a doctor; maybe a decreased dose will lower a degree of the side effects.

If you have an allergic reaction during the treatment, stop taking Cephalexin and go to a doctor. If an intolerance of this antibiotic is detected, replace it by a drug from another medical group.